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Ingredient analysis · Hazard 5/10

Octisalate.

Also known as: ethylhexyl salicylate, 2-ethylhexyl salicylate, octyl salicylate

A chemical UV filter that absorbs UVB radiation and is commonly used as a secondary sunscreen agent to boost SPF values. Octisalate also acts as a solvent for other UV filters like avobenzone.

Hormone Disruptor
Hazard score

By the numbers.

1 = low concern, 10 = avoid.

Hazard Score
5
Moderate Concern
Frequency risk

Risk by usage.

How risk shifts depending on how often you use products with Octisalate.

1-2x per week

Low risk from incidental sun protection use.

Daily use

Daily application leads to systemic absorption. Mineral filters are preferred for everyday use.

2+ times daily

Moderate concern. Use zinc oxide-based sunscreens for frequent reapplication.

Health risks

What the research says.

Absorbed through the skin at levels exceeding FDA safety thresholds in clinical studies.

JAMA, 2020 — systemic absorption of sunscreen active ingredients

Weak endocrine disruption potential observed in cell-based studies.

Can cause allergic contact dermatitis and photoallergic reactions in susceptible individuals.

Regulations

Global status.

How octisalate is regulated in cosmetics around the world.

Restricted in 11

100% of countries with data ban or restrict this ingredient

🇺🇸USA
Restricted
Details

Max 5% as OTC sunscreen active.

🇪🇺EU
Restricted
Details

Max 5% as UV filter (Annex VI).

🇬🇧UK
Restricted
Details

Max 5% as UV filter.

🇨🇦Canada
Restricted
Details

Max 5% as UV filter.

🇯🇵Japan
Restricted
Details

Permitted with limits under MHLW positive list.

🇰🇷S. Korea
Restricted
Details

Max 5% as UV filter.

🇦🇺Australia
Restricted
Details

Max 5% as active sunscreen (TGA).

🇨🇳China
Restricted
Details

Max 5% per Safety Technical Standards.

🇧🇷Brazil
Restricted
Details

Max 5% per ANVISA.

🇮🇳India
Restricted
Details

Permitted with limits.

🌏ASEAN
Restricted
Details

Max 5%, aligned with EU.

Why it’s used

The reason brands include it.

Absorbs UVB rays, boosts SPF values, and helps dissolve and stabilize other sunscreen active ingredients in the formulation.

13

products in our database

7

brands use it

3

product categories

Better alternatives exist. Brands choose octisalate because it’s cheap and effective, but safer options like zinc oxide, titanium dioxide, non-nano mineral sunscreens deliver similar results without the health concerns.

Categories

Octisalate in product types.

Click a category to see every product containing octisalate.

Products Containing Octisalate

These popular products list octisalate in their ingredient labels. Tap any card to see the full breakdown.

Found in 13 products across 7 brands

And 1 more product in our database.

The worst offender

Compared to Numbrrrz.

Here’s how the lowest-scoring product containing octisalate compares.

View full ingredient analysis for Blistex Medicated Lip Balm SPF 15
Blistex Medicated Lip Balm SPF 15

Blistex Medicated Lip Balm SPF 15

Blistex

Ingredients15
Flagged12
Safety Score1/10
Numbrrrz Organic Lip Balm

Numbrrrz

Organic Lip Balm

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Safe alternatives

What to use instead.

zinc oxide
titanium dioxide
non-nano mineral sunscreens

What Numbrrrz uses instead

Numbrrrz products contain no octisalate or chemical UV filters. Our lip balms protect with Organic Coconut Oil, Organic Jojoba Oil, Organic Beeswax, and Vitamin E — no sunscreen chemicals needed for daily lip care.

Questions

Quick answers.

Is octisalate dangerous?
Octisalate is considered one of the lower-risk chemical UV filters, but it is still absorbed systemically at levels the FDA considers above its safety threshold. Mineral sunscreens avoid this concern entirely.
Why is octisalate often paired with other UV filters?
Octisalate only absorbs UVB, not UVA. It is almost always combined with other filters for broad-spectrum coverage and also helps dissolve less-soluble filters like avobenzone.
Is octisalate absorbed into the bloodstream?
Yes. A 2020 JAMA study found that octisalate was absorbed into the bloodstream at levels exceeding the FDA's safety threshold of 0.5 ng/mL after just one day of normal sunscreen application. The long-term effects of this systemic absorption are still unknown.
What are other names for octisalate on labels?
Octisalate may appear as 'ethylhexyl salicylate,' '2-ethylhexyl salicylate,' or 'octyl salicylate' on sunscreen and SPF product labels. It is one of the most common secondary UV filters in chemical sunscreen formulations.
Can octisalate cause allergic reactions?
Yes. Octisalate can cause allergic contact dermatitis and photoallergic reactions in some individuals. People with salicylate sensitivity or aspirin allergies may be at higher risk for reactions to this ingredient.
Does Numbrrrz use octisalate?
No. Numbrrrz contains no octisalate or any chemical UV filters. Our lip balms use Organic Coconut Oil, Organic Jojoba Oil, Organic Beeswax, and Vitamin E — no sunscreen chemicals that could trigger allergic reactions or be absorbed systemically.
Related comparisons

How these brands stack up.

Brands that use octisalate — see how they compare.

Choose clean

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